The present invention provides compounds that are irreversible inhibitors of tyrosine kinases. Also provided is a method of treating cancer, restenosis, atherosclerosis, endometriosis, and psoriasis and a pharmaceutical composition that comprises a compound that is an irreversible inhibitor of tyrosine kinases.

La présente invention fournit les composés qui sont les inhibiteurs irréversibles des kinases de tyrosine. En outre fournie est une méthode de traiter le cancer, le restenosis, l'athérosclérose, l'endométriose, et le psoriasis et une composition pharmaceutique qui comporte un composé qui est un inhibiteur irréversible des kinases de tyrosine.

 
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