The above-discussed and other drawbacks and deficiencies of prior art are overcome or alleviated by the closed system access device of the present invention. The closed system access device provides a tool for managing fluid transactions that ensures the sterility of a needle, prevents exposure to toxic or hazardous medicines, and protects against needle stick by completely encasing the needle in a housing. The device allows for a protected needle withdrawal of blood, injection of medicine and transfer of fluids by use of an unexposed, internal needle which inhibits contamination and prevents contact with the transferred blood and/or medicine.