The invention relates to a method of altering hypothalamic function in an
individual. The method comprises nasally administering a human
vomeropherin, e.g. a 19-nor cholane steroid, or a pharmaceutical
composition containing a vomeropherin, such that the vomeropherin binds to
a specific neuroepithelial receptor. The steroid or steroids is/are
preferably administered in the form of a pharmaceutical composition
containing one or more pharmaceutically acceptable carriers. Other
embodiments of the invention include pharmaceutical compositions
containing the steroids.