Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

Inibidores da proteína de transferência do ester do cholesteryl, composições pharmaceutical que contêm tais inibidores e o uso de tais inibidores elevate determinados níveis de lipid do plasma, including o lipoprotein-cholesterol elevado da densidade e abaixar determinados outros níveis de lipid do plasma, tais como o LDL-lDL-cholesterol e os triglycerides e tratar conformemente as doenças que exacerbated por níveis baixos do cholesterol de HDL e/ou por níveis elevados do LDL-lDL-cholesterol e dos triglycerides, tais como o atherosclerosis e doenças cardiovascular em alguns mamíferos, including seres humanos.

 
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