A phenothiazine, acridan, acridone oxime, acridone hydrazone and dibenzodiazepine derivative represented by formula (I) ##STR1## effective against diseases in which histamine, leukotrienes, etc. participate and effective in preventing or treating diseases in which chemical mediators such as histamine and leukotrienes participate, for example, asthma, allergic rhinitis, atopic dermatitis, urticaria, hay fever, gastrointestinal allergy and food allergy.

Phenothiazine, acridan, acridoneoxime, acridonehydrazone en dibenzodiazepinederivaat wordt vertegenwoordigd dat door formule (I) ## STR1 ## efficiƫnt tegen ziekten waarin histamine, leukotrienes, enz. neem en efficiƫnt in het verhinderen van of het behandelen van ziekten deel waaraan de chemische bemiddelaars zoals histamine en leukotrienes, bijvoorbeeld, astma, allergisch Rhinitis, atopic dermatitis, urticaria, hooikoorts, gastro-intestinale allergie en voedselallergie deelnemen.

 
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