Certain N-substituted indoles having aryloxyacetic acid, substituents are agonists or partial agonists of PPAR gamma, and are useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR mediated diseases, disorders and conditions.

Bestimmte N-Ersatzindoles, die aryloxyacetic Säure haben, Substituenten sind Agonists oder teilweise Agonists des PPAR Gammas, und sind in der Behandlung, die Steuerung oder die Verhinderung Nichtinsulin des abhängigen Diabetes mellitus (NIDDM) nützlich, des hyperglycemia, des dyslipidemia, der Hyperlipidemie, des hypercholesterolemia, des hypertriglyceridemia, der Atherosclerose, der Korpulenz, des Gefäßrestenosis, der Entzündung und anderer PPAR vermittelter Krankheiten, Störungen und Bedingungen.

 
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