The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosage sufficient to inhibit cell mitosis. The application discloses novel compounds used in the methods.

L'applicazione rileva i metodi di trattare le malattie mammifere caratterizzate dalla mitosi anormale delle cellule amministrando i derivati di estradiol compreso quelli che contengono i motivi strutturali di combretastatin o della colchicina A-4 le formule generali trovate sotto in un dosaggio sufficiente per inibire la mitosi delle cellule. L'applicazione rileva i residui del romanzo usati nei metodi.
 
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> Diyne-containing (co)polymer, processes for producing the same, and cured film

> Catalytic production of olefins at high methanol partial pressures
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