An implant is provided as a solid aggregate of bone-derived elements, e.g., particles, powders, granules, fibers, strips and/or large pieces of xenogenic, allogenic, transgenic, tissue engineered or autologous cortical and/or cancellous bone, employing as binding agent for the bone-derived elements a precipitate or crystalline bridge of metal oxide, metal hydroxide, metal salt of an inorganic acid, metal salt of an organic acid, metal-containing silica based glass, or mixture thereof, the binding agent possessing at least slight solubility in polar solvent, adjacent bone-derived elements being bonded to each other through engagement with particles or bridge-like structures of bonding agent.

_ un implant essere forn come un solido complesso osso-deriv elemento, per esempio, particella, polvere, granello, fibra, striscia e/o gran parte xenogenic, allogenico, transgenic, tessuto costru o autologous corticale e/o cancellous osso, impieg come binding agente per osso-deriv elemento un precipitato o cristallino ponticello metallo ossido, metallo idrossido, metallo sale un inorganico acido, metallo sale un organico acido, metallo-conten silicone bas vetro, o miscela di ciò, binding agente possed almeno leggero solubilità polare solvente, adiacente osso-deriv elemento essere leg l'un l'altro attraverso aggancio con particella o ponticello-come struttura bonding agente.