The present invention relates to a method of disinfecting immobilized biocatalysts in which the extinguishing of microbes adhering to carriers without lowering the activity of immobilized biocatalysts by irradiating ultraviolet light to immobilized biocatalysts at the illuminating power of less than 0.5mW/cm.sup.2, and to a reactor provided with fluidized chamber wherein a column chamber with outflow-preventing net is connected with an end of fluidized chamber, and an inner tube with an outflow-preventing net at the head opening and at the same time movable in the fluidized chamber is connected with a column chamber, and at the other side of the fluidized chamber a washing gateway with an outflow-preventing net is connected so as to be able to be washing, disinfecting, adsorbing and eluting of reaction continuously.

A invenção atual relaciona-se a um método de disinfecting os biocatalysts immobilized em que extinguir dos micróbios que aderem aos portadores sem abaixar a atividade de biocatalysts immobilized irradiating a luz ultravioleta aos biocatalysts immobilized no poder iluminando de menos do que 0.5mW/cm.sup.2, e a um reator fornecido com a câmara fluidized wherein uma câmara da coluna com rede outflow-impedindo é conectada com uma extremidade da câmara fluidized, e um tubo interno com uma rede outflow-impedindo na abertura principal e móvel na câmara fluidized é conectado ao mesmo tempo com uma câmara da coluna, e no outro lado da câmara fluidized uma passagem de lavagem com uma rede outflow-impedindo é conectada para poder seja de lavagem, disinfecting, adsorbing e eluting da reação continuamente.