Compounds of the formula ##STR1## and salts thereof wherein the substituents are defined as in accordance with the specification useful for the treatment of tumor growth, osteoporosis, inflammation and cardiovascular disorders.

Compostos do ## do ## STR1 da fórmula e dos sais disso wherein os substituents são definidos como de acordo com a especificação útil para o tratamento do crescimento do tumor, do osteoporosis, do inflammation e de disorders cardiovascular.