A nutritional composition which contains slightly negatively charged non-digestible polysaccharides having a molecular weight of 8 kD to 40,000 kD, characterized in that the rise in the viscosity of the composition caused by the polysaccharides is less than 20 mpa.multidot.s. This nutritional composition is used to reduce the uptake of high molecular weight substances, allergens and microorganisms through the intestinal wall, more particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the intestinal wall, ore particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the tight junctions in the intestines. The nutritional compositions can be used to prevent or to treat allergies, allergic reactions, sepsis and inflammatory processes, such as those which can arise under emotional and physical stress, ischaemia, reperfusion damage during and after operations, following radiation treatment and/or chemotherapy of cancer patients and in the case of inflammatory intestinal diseases, diarrhoea and allergies.

Uma composição nutritiva que contenha os polysaccharides non-digestible ligeiramente negativamente carregados que têm um peso molecular do kD 8 ao kD 40.000, caracterizada que a ascensão na viscosidade da composição causada pelos polysaccharides é menos de 20 mpa.multidot.s. Esta composição nutritiva é usada reduzir o uptake de substâncias elevadas, allergens e microorganisms do peso molecular através da parede intestinal, para reduzir mais particularmente particularmente o transporte de substâncias elevadas do peso molecular, os allergens e os microorganisms através da parede intestinal, o minério para reduzir o transporte de substâncias elevadas do peso molecular, os allergens e os microorganisms através das junções apertadas nos intestines. As composições nutritivas podem ser usadas impedir ou tratar allergies, reações allergic, sepsis e processos inflammatory, tais como aqueles que pode se levantar sob o stress emocional e físico, ischaemia, os danos do reperfusion durante e após operações, depois do tratamento de radiação e/ou do chemotherapy de pacientes do cancer e no exemplo de doenças, do diarrhoea e de allergies intestinal inflammatory.

 
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> Oligosaccharide derivatives and process for producing the same

> Method for the production of spherical microparticles consisting totally or partly of at least one water insoluble polyglucan containing branches and microparticles produced according to said method

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