Production and use of derivatized homoserine lactones

   
   

The present invention provides analogues of autoinducer molecules that are derivatized to allow their attachment to other molecules and surfaces. Libraries of the autoinducer analogues are also contemplated. Also provided are methods for using the compounds of the invention to produce compositions, such as immunoconjugates, antibodies and vaccines, which are useful for treating and preventing disease states in a subject. The compositions of the invention are also useful in various assays, including assessing the autoinducer load in a subject.

A invenção atual fornece analogues das moléculas do autoinducer que derivatized para permitir seu acessório a outras moléculas e superfícies. As bibliotecas dos analogues do autoinducer são contempladas também. São fornecidos também os métodos para usar os compostos da invenção produzir as composições, tais como immunoconjugates, os antibodies e as vacinas, que são úteis para tratar e impedir estados da doença em um assunto. As composições da invenção são também úteis em vários assays, including avaliar a carga do autoinducer em um assunto.

 
Web www.patentalert.com

< Fluoroscopic tracking and visualization system

< Compositions and methods for enhancing receptor-mediated cellular internalization

> Process for graphic visualization and diagnosis of thrombi by means of nuclear spin tomography with use of particulate contrast media

> Methods of using adeno-associated virus rep protein

~ 00103