The present invention provides novel physiologically active protein
molecules originating in mammals, which are specifically expressed in
arteriosclerosis and/or coronary restenosis, and are predicted to relate
closely to the onset and progress of these diseases; DNAs encoding the
protein molecules; antibodies reactive with the molecules; and
pharmaceutical compositions comprising the above protein molecule or the
antibody. The protein molecules, DNAs, and antibodies are useful for
treating and preventing arteriosclerosis.
A invenção atual fornece as moléculas physiologically ativas da proteína da novela que originam nos mamíferos, que são expressados especificamente no arteriosclerosis e/ou no restenosis coronary, e é predita para relacionar-se pròxima ao início e ao progresso destas doenças; DNAs que codifica as moléculas da proteína; antibodies reactive com as moléculas; e composições pharmaceutical que compreendem a molécula acima da proteína ou o antibody. As moléculas, o DNAs, e os antibodies da proteína são úteis para tratar e impedir o arteriosclerosis.