Compositions of the present invention comprise chlorinated heterocyclic
compounds, including racemic monochloroflosequinan, purified enantiomers
of monochloroflosequinan and the sulfone derivative of
monochloroflosequinan. The methods of the present invention comprise the
synthesis of racemic monochloroflosequinan and derivatives thereof,
including the sulfone derivative. Intermediates in the synthesis are also
provided. The methods further comprise the synthesis of enantiomers of
monochloroflosequinan.
As composições da invenção atual compreendem compostos heterocyclic chlorinated, including enantiomers monochloroflosequinan, purified racemic de monochloroflosequinan e o derivative do sulfone de monochloroflosequinan. Os métodos da invenção atual compreendem a síntese de monochloroflosequinan racemic e de derivatives disso, including o derivative do sulfone. Os intermediários na síntese são fornecidos também. Os métodos mais adicionais compreendem a síntese dos enantiomers de monochloroflosequinan.
