Chlorinated heterocyclic compounds and methods of synthesis

   
   

Compositions of the present invention comprise chlorinated heterocyclic compounds, including racemic monochloroflosequinan, purified enantiomers of monochloroflosequinan and the sulfone derivative of monochloroflosequinan. The methods of the present invention comprise the synthesis of racemic monochloroflosequinan and derivatives thereof, including the sulfone derivative. Intermediates in the synthesis are also provided. The methods further comprise the synthesis of enantiomers of monochloroflosequinan.

As composições da invenção atual compreendem compostos heterocyclic chlorinated, including enantiomers monochloroflosequinan, purified racemic de monochloroflosequinan e o derivative do sulfone de monochloroflosequinan. Os métodos da invenção atual compreendem a síntese de monochloroflosequinan racemic e de derivatives disso, including o derivative do sulfone. Os intermediários na síntese são fornecidos também. Os métodos mais adicionais compreendem a síntese dos enantiomers de monochloroflosequinan.

 
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