Delivery systems for periadventitial delivery for treatment of restenosis and anastomotic intimal hyperplasia

   
   

The invention provides methods for treating injuries to one or more internal structures of a subject by administering a drug delivery vehicle to an external surface of the injured structure. The drug delivery vehicle substantially adheres to the site of administration and provides for the release of a bioactive agent that reduces or prevents further injury to the internal structure by disease processes, such as hyperplasia.

A invenção fornece métodos tratando os ferimentos a um ou mais estrutura interna de um assunto administrando um veículo da entrega da droga a uma superfície externa da estrutura ferida. O veículo da entrega da droga adere substancialmente ao local da administração e fornece para a liberação de um agente bioactive que reduza ou impeça ferimento mais adicional à estrutura interna por processos da doença, tais como a hiperplasia.

 
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