There is provided a suppository comprising at least one biocompatible
polymer, wherein the biocompatible polymer is essentially
non-biodegradable, and wherein the suppository essentially does not swell
when contacted with an aqueous fluid. The suppository may further comprise
a plurality of open cells at least partly separated from one another by an
interpenetrating matrix comprising at least one biocompatible polymer in
branched or crosslinked form. The plurality of interlinked, open cells are
capable of containing an aqueous fluid, and the permeability of the
suppository ensures that entry of body fluids into the open cells under
practical circumstances occurs essentially without dehydration of mucousal
membrane tissue contacting the suppository. The suppository furthermore
preferably comprises a controlled release formulation.
