The present invention provides a method of nucleic acid, including DNA,
immunization of a host, including humans, against disease caused by
infection by a strain of Chlamydia, specifically C. pneumoniae, employing
a vector, containing a nucleotide sequence encoding a CPN100605
polypeptide of a strain of Chlamydia pneumoniae and a promoter to effect
expression of the CPN100605 polypeptide in the host. Modifications are
possible within the scope of this invention.