In summary of this disclosure, the present invention provides a method of
nucleic acid, including DNA, immunization of a host, including humans,
against disease caused by infection by a strain of Chlamydia, specifically
C. pneumoniae, employing a vector, containing a nucleotide sequence
encoding an POMP91B precursor protein of a strain of Chlamydia pneumoniae
and a promoter to effect expression of the POMP91B precursor gene in the
host. Modifications are possible within the scope of this invention.