Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same

   
   

The present invention is directed to polymeric prodrug transport forms and methods of making and using the same. In one preferred aspect, the prodrugs are of the formula: ##STR1## wherein G is a polymeric residue; Z is one of: ##STR2## and B is a residue of a biologically active amine-containing moiety or a hydroxyl-containing moiety.

A invenção atual é dirigida aos formulários do transporte do prodrug e aos métodos de fazer polymeric e de usar o mesmo. Em um preferiu o aspecto, os prodrugs são da fórmula: ## do ## STR1 wherein G é um resíduo polymeric; Z é um de: ## do ## STR2 e B é um resíduo de um moiety amine-contendo biològica ativo ou de um moiety hydroxyl-contendo.

 
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