DNAs encoding canine Cathepsin S have been cloned and characterized. The
recombinant protein is capable of forming biologically active protein. The
cDNA's have been expressed in recombinant host cells that produce active
recombinant protein. The recombinant protein is also purified from the
recombinant host cells. In addition, the recombinant host cells are
utilized to establish a method for identifying modulators of the receptor
activity, and receptor modulators are identified.
DNAs que codifica o cathepsin canine S cloned e foi caracterizado. A proteína recombinant é capaz de dar forma à proteína biològica ativa. Os DNA'S foram expressados nas pilhas de anfitrião recombinant que produzem a proteína recombinant ativa. A proteína recombinant purified também das pilhas de anfitrião recombinant. Além, as pilhas de anfitrião recombinant são utilizadas para estabelecer um método para identificar moduladores da atividade do receptor, e os moduladores do receptor são identificados.
