Phosphopeptides containing the Ser(P) cluster sequence motif
Ser(P)-Ser(P)-Ser(P)-Glu-Glu- can stabilize their own weight in amorphous
calcium phosphate (ACP) and amorphous calcium fluoride phosphate (ACFP).
The amorphous phases stabilized by the phosphopeptides are an excellent
delivery vehicle to co-localise calcium, fluoride, and phosphate ions at
the tooth surface in a slow-release amorphous form producing superior
anticaries efficacy. These amorphous phases stabilized by the
phosphopeptides also have utility as dietary supplements to increase
calcium bioavailability and to help prevent diseases associated with
calcium deficiencies.
