Methods, systems, and kits for intravascular nucleic acid delivery

   
   

Nucleic acid transfection of vascular smooth muscle cells is enhanced by the application of vibrational energy to the cells. By applying vibrational energy at frequency in the range from 1 kHz to 10 MHz and at an intensity in the range from 0.01 W/cm.sup.2 to 100 W/cm.sup.2, significant enhancement of the uptake of nucleic acids into vascular smooth muscle cells can be achieved.

El transfection del ácido nucleic de las células lisas vasculares del músculo es realzado por el uso de la energía vibratoria a las células. Aplicando energía vibratoria en la frecuencia en la gama a partir de 1 kilociclo a 10 megaciclos y en una intensidad en la gama a partir de 0.01 W/cm.sup.2 a 100 W/cm.sup.2, el realce significativo del uptake de ácidos nucleic en las células lisas vasculares del músculo puede ser alcanzado.

 
Web www.patentalert.com

< Solid preparations for oral administration of drugs relating to genes

< Method and system for analyzing chromatograms

> Method and apparatus for determining gene expression levels

> Immunoassay for LSD and 2-oxo-3-hydroxy-LSD

~ 00133