Small and intermediate conductance, calcium-activated potassium channels and uses thereof

   
   

This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic acids encoding calcium-activated potassium channel proteins. The invention also provides methods and compositions for assaying compounds which increase or decrease potassium ion flux through a calcium-activated potassium channel.

Cette invention concerne la petite et intermédiaire conductibilité, protéines calcium-activées de canal de potassium. Plus spécifiquement, l'invention concerne des compositions et les méthodes pour préparer et détecter les protéines calcium-activées de canal de potassium et les acides nucléiques codant le potassium calcium-activé creusent des rigoles des protéines. L'invention fournit également des méthodes et les compositions pour l'analyse compose qui augmentent ou diminuent le flux d'ion de potassium par un canal calcium-activé de potassium.

 
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