Methods of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth

   
   

Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which involves detecting the presence of small intestinal bacterial overgrowth (SIBO) in a human subject having at least one symptom associated with a suspected diagnosis of any of those diagnostic categories. Also disclosed is a method of treating these disorders, and other disorders caused by SIBO, that involves at least partially eradicating a SIBO condition in the human subject. The method includes administration of anti-microbial or probiotic agents, or normalizing intestinal motility by employing a prokinetic agent. The method improves symptoms, including hyperalgesia related to SIBO and disorders caused by SIBO. Also disclosed is a kit for the diagnosis or treatment of irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, or Crohn's disease.

É divulgado um método de diagnosticar o syndrome irritable do bowel, fibromyalgia, syndrome crônico da fatiga, depression, disorder da atenção deficit/hyperactivity, doenças autoimmune, tais como o sclerosis múltiplo e o erythematosus systemic do lupus, ou a doença de Crohn, que envolve detectar a presença do overgrowth bacteriano intestinal pequeno (SIBO) em um assunto humano que tem ao menos um sintoma associado com um diagnóstico suspeitado de algumas daquelas categorias diagnósticas. São divulgados também um método de tratar estes disorders, e outros disorders causados por SIBO, que envolve ao menos parcialmente eradicating uma condição de SIBO no assunto humano. O método inclui a administração de agentes anti-microbial ou probiotic, ou de normalizar o motility intestinal empregando um agente prokinetic. O método melhora sintomas, including a hiperalgesia relacionada a SIBO e os disorders causados por SIBO. É divulgado também um jogo para o diagnóstico ou o tratamento do syndrome irritable do bowel, do fibromyalgia, do syndrome crônico da fatiga, do depression, do disorder da atenção deficit/hyperactivity, de doenças autoimmune, ou de doença de Crohn.

 
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