Phosphorothioate oligonucleotides having modified internucleoside linkages

   
   

Novel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are phosphorothioate oligonucleotides wherein the 5'-terminal internucleoside linkage or the 5'- and 3'-terminal linkages are modified.

De nieuwe mimische samenstellingen die en/of moduleren de activiteit van wild-type nucleic zuren. In het algemeen, zijn de samenstellingen phosphorothioate oligonucleotides waarin de 5'-eindinternucleosideaaneenschakeling of 5 ' - en de 3'-eindaaneenschakelingen worden gewijzigd.

 
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> Coating systems containing modified crosslinkers

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