Methods for therapy of neurodegenerative disease of the brain

   
   

A specific clinical protocol for use toward therapy of defective, diseased and damaged neurons in the mammalian brain, of particular usefulness for treatment of neurodegenerative conditions such as Parkinson's disease and Alzheimer's disease. The protocol is practiced by directly delivering a definite concentration of recombinant neurotrophin, into a targeted region of the brain using an expression vector. The neurotrophin is delivered to, or within close proximity of, identified defective, diseased or damaged brain cells. The method stimulates growth of targeted neurons, and reversal of functional deficits associated with the neurodegenerative disease being treated.

Un protocolo clínico específico para el uso hacia la terapia de neuronas defectuosas, enfermas y dañadas en el cerebro mamífero, de la utilidad particular para el tratamiento de condiciones neurodegenerative tales como enfermedad de Parkinson y enfermedad de Alzheimer. El protocolo es practicado directamente entregando una concentración definida del neurotrophin recombinant, en una región apuntada del cerebro usando un vector de la expresión. El neurotrophin se entrega, o dentro de proximidad cercana, de células de cerebro de defectuosas, enfermas o dañadas identificadas. El método estimula el crecimiento de neuronas apuntadas, y la revocación del déficit funcional asociado a la enfermedad neurodegenerative que es tratada.

 
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