Prophylactic and therapeutic monoclonal antibodies

   
   

In this application are described monoclonal antibodies which recognize E3 glycoprotein of alphavirus and epitopes recognized by these monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of alphavirus infections in vitro and in vivo.

In dit is toepassing beschreven monoclonal antilichamen die E3 glycoproteïne van alphavirus erkennen en epitopes die door deze monoclonal antilichamen wordt erkend. Op voorwaarde dat ook mengsels van antilichamen van de onderhavige uitvinding, evenals methodes zijn om individuele antilichamen of mengsels daarvan voor de opsporing, de preventie, en/of de therapeutische behandeling van alphavirusbesmettingen te gebruiken in vitro en in vivo.

 
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