Transgenic non-human mammals expressing the human complement inhibitor (DAF/CD55)

   
   

This invention provides transgenic mammals other than man carrying the gene of the human complement inhibitor (DAF/CD55) and expressing the human complement inhibitor in their organs and tissues, particularly in their endothelial cells. This invention provides nonhuman transgenic mammals useful as laboratory animals in the medical and pharmacological fields and/or sources of organs, tissues, cells and the like for medical treatment of man.

Cette invention fournit les mammifères transgéniques autres que l'homme portant le gène de l'inhibiteur humain de complément (DAF/CD55) et exprimant l'inhibiteur humain de complément en leurs organes et tissus, en particulier en leurs cellules endothéliales. Cette invention fournit les mammifères transgéniques non humains utiles comme animaux de laboratoire dans les domaines et/ou les sources médicaux et pharmacologiques des organes, des tissus, des cellules et des semblables pour le traitement médical de l'homme.

 
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