Methods for tissue specific synthesis of protein in eggs of transgenic hens

   
   

Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein the transgene is expressed in the hen's oviduct and the transgene product is secreted in the hen's eggs and/or those of her offspring. In a preferred embodiment, the transgene product is secreted in the egg white.

Los vectores y los métodos se proporcionan para introducir el material genético en las células de un pollo o de otras especies aviares. Más particularmente, los vectores y los métodos se proporcionan para transferir un transgene a una célula embrionaria del pollo, para crear una gallina transgenic en donde el transgene se expresa en el oviducto de la gallina y el producto del transgene se secreta en los huevos y/o los de gallina de su descendiente. En una encarnación preferida, el producto del transgene se secreta en el blanco del huevo.

 
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