Devices are provided which include supports upon which one or more
ion-exchange materials can be disposed for purifying a sample. In various
embodiments, the supports include a plurality of deformable members, for
example, petal-shaped purification members, that provide binding sites for
ion-exchange material and optionally biochemical species, chemicals,
salts, or other materials. An apparatus and method are also provided for
the insertion and removal of the purification members into respective
wells of a multi-well microplate.