The present invention relates to AUR1 and/or AUR2 polypeptides, nucleic
acids encoding such polypeptides, cells, tissues and animals containing
such nucleic acids, antibodies to such polypeptides, assays utilizing such
polypeptides, and methods relating to all of the foregoing. Methods for
treatment, diagnosis, and screening are provided for AUR1 and/or AUR2
related diseases or conditions characterized by an abnormal interaction
between a AUR1 and/or AUR2 polypeptide and a AUR1 and/or AUR2 binding
partner.