Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting .beta.-amyloid peptide release and/or its synthesis by use of such compounds

   
   

Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Se divulgan los compuestos que inhiben el lanzamiento del peptide del beta.-amiloide y/o su síntesis, y, por consiguiente, tienen utilidad en la enfermedad de Alzheimer que trata. También se divulgan las composiciones farmacéuticas que abarcan un compuesto que inhiba el lanzamiento del peptide del beta.-amiloide y/o su síntesis así como los métodos para tratar la enfermedad de Alzheimer prophylactically y terapéutico con tales composiciones farmacéuticas.

 
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> Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components

> Muteins of hypoxia inducible factor alpha and methods of use thereof

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