A method of fabricating polynucleotide arrays includes dissolving a
nucleotide monomer, oligonucleotide, or polynucleotide in a solvent
containing ionic liquid and depositing the resulting solution on an array
substrate. The method has particular application to fabrication of an
addressable array of polynucleotides on a substrate that carries substrate
bound moieties each with a hydroxyl group. The process may be repeated at
specific locations on the array to elongate the polynucleotide deposited
on the array.