The present invention relates to novel 3-methylidenyl-2-indolinone
compounds and physiologically acceptable salts and prodrugs thereof which
modulate the activity of protein kinases and therefore are expected to be
useful in the prevention and treatment of protein kinase related cellular
disorders such as cancer.
A invenção atual relaciona-se aos compostos da novela 3-methylidenyl-2-indolinone e os sais e os prodrugs physiologically aceitáveis disso que modulam a atividade de kinases de proteína e conseqüentemente esperam-se ser úteis na prevenção e no tratamento de disorders celulares relacionados do kinase de proteína tais como o cancer.