Substituted cyclic amine metalloprotease inhibitors

   
   

The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). ##STR1## Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.

L'invenzione fornisce i residui che sono utili come inibitori dei metalloproteases e che sono efficaci nelle circostanze trattanti caratterizzate da attività eccedente di questi enzimi. In particolare, la presente invenzione riguarda un residuo che ha una struttura secondo la formula (i). ## del ## STR1 Inoltre sono rilevati i residui, le composizioni farmaceutiche ed i metodi di trattare le malattie caratterizzate da attività di metalloprotease usando questi residui o le composizioni farmaceutiche che li contengono.

 
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< 4-[(8-ETHYNYL, 8-VINYL OR 8-ETHYNYL-METHYL)-6-CHROMANOYL]-BENZOIC AND 2-[4-[(8-ETHYNYL, 8-VINYL OR 8-ETHYNYL-METHYL)-6-CHROMANOYL]-PHENYL]-ACETIC ACID, THEIR ESTERS AND SALTS HAVING CYTOCHROME P450RAI INHIBITORY ACTIVITY

< Mammalian adhesion protease peptides

> Use of fumaric acid derivatives for treating mitochondrial diseases

> Estrogen receptor modulators

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