Methods for treating conditions or disorders which can be alleviated by
reducing food intake are disclosed which comprise administration of an
effective amount of an exendin or an exendin agonist, alone or in
conjunction with other compounds or compositions that affect satiety. The
methods are useful for treating conditions or disorders, including
obesity, Type II diabetes, eating disorders, and insulin-resistance
syndrome. The methods are also useful for lowering the plasma glucose
level, lowering the plasma lipid level, reducing the cardiac risk,
reducing the appetite, and reducing the weight of subjects.
Pharmaceutical compositions for use in the methods of the invention are
also disclosed.