Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents

   
   

The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines of the formula ##STR1## where Z is selected from the group consisting of --S(O).sub.2 --, and --C(O)--.

A invenção atual é dirigida aos derivatives do acyl e do sulfonyl de 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines do ## do ## STR1 da fórmula onde Z é selecionado do grupo que consiste -- S(O).sub.2 --. e -- c(o) --

 
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