Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers

   
   

A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnostic and/or therapeutic target for cancers. The 158P1D7 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.

Un gene de la novela (señalado 158P1D7) y su proteína codificada se describen. Mientras que 158P1D7 exhibe la expresión específica del tejido fino en tejido fino normal del adulto, aberrantly se expresa en cánceres múltiples incluyendo dispuesto en la tabla 1. Por lo tanto, 158P1D7 proporciona una blanco de diagnóstico y/o terapéutica para los cánceres. El gene 158P1D7 o el fragmento de eso, o su proteína codificada o un fragmento de eso, se pueden utilizar para sacar una inmunorespuesta.

 
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> Method for producing hybridization complexes whose stability is substantially independent of the base composition of two hybridized nucleic acid molecules

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