The present invention relates to the field of metabolic research. Metabolic
disorders, such as obesity, are a public health problem that is serious
and widespread. Adipsin polypeptides have been identified that are
believed to be beneficial in the treatment of metabolic disorders. These
compounds should be effective for reducing body mass and for treating
metabolic-related diseases and disorders. These metabolic-related diseases
and disorders include hyperlipidemias, atherosclerosis, insulin
resistance, diabetes, and hypertension.