Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof

   
   

Compounds of Formula (IA) and Formula (IB) 1 wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as defined herein for Formula (IA) or Formula (IB), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

I residui della formula (IA) e della formula (IB) 1 in cui R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 e R.sup.6 sono come definiti qui per la formula (IA) o la formula (IB), o un tautomer, prodrug, solvate, o salano di ciĆ²; le composizioni farmaceutiche che contengono tali residui ed i metodi di modulazione della funzione glucocorticoide del ricevitore ed i metodi di trattare disease-dichiarare o le circostanze mediate dal ricevitore glucocorticoide funzionano o caratterizzato tramite i processi infiammatori, allergici, o proliferative in un paziente usando questi residui.

 
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