In summary of this disclosure, the present invention provides a method of
nucleic acid, including DNA, immunization of a host, including humans,
against disease caused by infection by a strain of Chlamydia, specifically
C. pneumoniae, employing a vector, containing a nucleotide sequence
encoding an 98 kDa putative outer membrane protein of a strain of
Chlamydia pneumoniae and a promoter to effect expression of the 98 kDa
putative outer membrane protein gene in the host. Modifications are
possible within the scope of this invention.