Method for purifying 5' -protected thymidines and novel derivatives thereof

   
   

This invention provides a method for efficiently purifying 5'-protected thymidines which cannot be efficiently purified by the prior art. Impurities can be separated by obtaining crystals including a carbonyl-containing solvent to provide a highly pure 5'-protected thymidine. Thus, this invention allows 5'-protected thymidines, which cannot be purified in an industrial scale by the prior art, to be easily provided with a high purity in a large scale.

Esta invenção fornece um método eficientemente purifying os thymidines 5'-protected que não podem eficientemente purified pela arte prévia. As impurezas podem ser separadas obtendo cristais including um solvente carbonyl-contendo para fornecer um thymidine 5'-protected altamente puro. Assim, esta invenção permite que os thymidines 5'-protected, que não podem purified em uma escala industrial pela arte prévia, sejam fornecidos fàcilmente com um purity elevado em uma escala grande.

 
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