Disclosed is a method and apparatus for accomplishing a noninvasive screen
for breast disease markers, including breast cancer markers and
cytologically abnormal cells. Intraductal fluid is noninvasively aspirated
using compression, heating and suction cycles. The removed sample is
thereafter assayed for the presence of cytologically abnormal cells and/or
one or more breast disease markers. In addition to the diagnostic
applications of the disclosed method and apparatus, a therapeutic
application is also contemplated wherein intraductal fluids are
noninvasively aspirated using compression, heating and suction cycles to
remove toxic buildups within the fluid.