The present invention relates to a method of in vitro spermatogenesis
involving Sertoli cells and diploid germ cells from a testis of a male
mammal to yield differentiated haploid spermatids. The present invention
also relates to spermatids produced by the method described above, where
the spermatids are haploid. The present invention also involves a method
of overcoming male infertility in mammals involving the use of the haploid
round spermatids produced by the in vitro spermatogenesis method of the
present invention. The present invention also relates to isolated haploid
spermatids.
