Provided by the present invention are topical formulations of Interleukin-11
and methods for treating a variety of disorders, including inflammatory bowel diseases
(e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious
colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis,
and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis,
atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis,
esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g.,
conjunctivitis, retinitis, and uveitis).
