The present invention provides methods and compositions for modification and
regulation of glucose and lipid metabolism, generally to reduce insulin resistance,
hyperglycemia, hyperinsulinemia, obesity, hyperlipidemia, hyperlipoprotein-emia
(such as chylomicrons, VLDL and LDL), and to regulate body fat and more generally
lipid stores, and, more generally, for the improvement of metabolism disorders,
especially those associated with diabetes, obesity and/or atherosclerosis.
