A topical insecticide is provided which can be safe to use and avoids many common
deleterious side effects of conventional topical insecticides. In one preferred
embodiment of the invention, the active ingredient of the insecticide formulation
is an amine derivative, having a nitro-methylene group, a nitroamino group or a
cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal
activity. One particularly suitable insecticide is 1-{(tetrahydro-3-furanyl)methyl}-2-nitro-3-methylguanidine(dinotefuran),
an aldulticide that will kill adult fleas combined with methoprene.