The application relates to compounds that are suitable as labelable precursors
for synthesis of 3-[18F]fluoro-3-deoxythymidine and
that have formula (1),
##STR1##
in which
- R denotes triphenylmethyl, triphenylmethyl substituted in the phenyl
group, trialkylmethyl, triphenylsilyl, triphenylsilyl substituted in the phenyl
group, or trialkylsilyl,
- R denotes R1SO2, where R1
is an unsubstituted or substituted C1 to C5 alkyl or
an unsubstituted or substituted phenyl, and
- R denotes C2 to C10 alkyloxycarbonyl,
with the exception of 3-N-Boc-1-(3-O-nosyl-5-O-trityl-2-deoxy--D-lyxofuranosy
The application also relates to a method for preparation of these compounds and
to the use of the same for synthesis of 3-[
18F]fluoro-3-deoxythymidine.
