The present invention provides for pyrazolopurine-based tricyclic
compounds having the formula (I), 1
wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as
described herein. The present invention further provides pharmaceutical
compositions comprising such compounds, as well as the use of such
compounds for treating inflammatory and immune diseases.