Aminothiazole compounds with N-containing cycloalkyl at the 2-amino
position which are represented by the Formula (I), or a pharmaceutically
acceptable prodrug of said compound, pharmaceutically active metabolite
or pharmaceutically acceptable salt of said compound, or metabolite
thereof, modulate and/or inhibit the cell proliferation and activity of
protein kinases. 1
The invention is also directed to the therapeutic or prophylactic use of
pharmaceutical compositions containing such compounds, and to methods of
treating malignancies and other disorders by administering effective
amounts of such compounds.
